WebJun 30, 2024 · Rifabutin is a red-violet powder soluble in chloroform and methanol, sparingly soluble in ethanol, and very slightly soluble in water (0.19 mg/mL). Its log P value (the base 10 logarithm of the partition coefficient between n-octanol and water) is 3.2 (n-octanol/water). Indications & Dosage INDICATIONS Webrifabutin (300 mg/day) decreased the AUC of indinavir by about 30% and increased the AUC of rifabutin by about 200% (see PRECAUTIONS-Drug Interactions). Nelfinavir: Coadministration of nelfinavir (750 mg q 8h for 8 days) and rifabutin (300 mg/day for 7–8 days) decreased the AUC and C. max. of nelfinavir by about 32% and 25%,
Systematic review of drug–drug interactions between rifamycins …
Rifabutin (Rfb) is an antibiotic used to treat tuberculosis and prevent and treat Mycobacterium avium complex. It is typically only used in those who cannot tolerate rifampin such as people with HIV/AIDS on antiretrovirals. For active tuberculosis it is used with other antimycobacterial medications. For latent tuberculosis it may be used by itself when the exposure was with drug-resistan… WebApr 1, 2024 · Incidence not known. Burning, dry, or itching eyes. discharge, excessive tearing. hoarseness. redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid. stomach cramps, pain, or tenderness. watery and severe diarrhea, which may also be bloody. Some side effects may occur that usually do not need medical attention. mmc pittsburgh
Rifabutin Uses, Side Effects & Warnings - Drugs.com
WebNov 29, 2024 · Rifabutin is an antibiotic which is used to treat (or prevent) serious infections caused by germs (bacteria) called mycobacteria. You can take rifabutin capsules either before or after meals. You will be asked to take one dose a day. Rifabutin can interfere with a number of other medicines - please let your doctor know which other medicines you ... Webrifabutin (300 mg/day) decreased the AUC of indinavir by about 30% and increased the AUC of rifabutin by about 200% (see PRECAUTIONS-Drug Interactions). Nelfinavir: … WebJun 7, 2024 · Rifabutin is an antibacterial prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the prevention of disseminated Mycobacterium avium … mmcp licensing